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Signs and symptoms
Clinical features and signs
In utero:
* Reduced fetal movement
* Frequent abnormal fetal position
* Occasional polyhydramnios (excessive amniotic fluid)
At birth:
* Often breech or caesarean births
* Lethargy
* Hypotonia
* Feeding difficulties (due to poor muscle tone affecting sucking reflex)
* Difficulties establishing respiration
* Hypogonadism
Infancy:
* Failure to thrive (continued feeding difficulties)
* Delayed milestones/intellectual delay
* Excessive sleeping
* Strabismus
* Scoliosis (often not detected at birth)
Childhood:
* Speech delay
* Poor physical coordination
* Hyperphagia (over-eating) from age 2 – 8 years. Note change from feeding difficulties in infancy
* Excessive weight gain
* Sleep disorders
* Scoliosis
Adolescence:
* Delayed puberty
* Short stature
* Obesity
* Extreme flexibility
Adulthood:
* Infertility (males and females)
* Hypogonadism
* Sparse pubic hair
* Obesity
* Hypotonia
* Learning disabilities/borderline intellectual functioning (but some cases of average intelligence)
* Prone to diabetes mellitus
* Extreme flexibility
General physical appearance (adults)
* Prominent nasal bridge
* Small hands and feet with tapering of fingers
* Soft skin, which is easily bruised
* Excess fat, especially in the central portion of the body
* High, narrow forehead
* Almond-shaped eyes with thin, down-turned lids
* Light skin and hair relative to other family members
* Lack of complete sexual development
* Frequent skin picking
* Striae
* Delayed motor development
AF Sitemap
- Education Topics
- Achievement Gap
- Alternative Education
- Assessment & Evaluation
- Educational Leadership
- Educational Philosophy
- Educational Research
- Educational Technology
- Educational Videos
- Education Economics
- Education Environment
- Education Issues
- Education Policy
- Education Psychology
- Education Reform
- Education Theory
- Education Worldwide
- Federal Education Legislation
- Homeless Education
- Homeschooling in the United States
- Migrant Education
- Neglected/Deliquent Students
- Pedagogy
- Sociology of Education
- Special Needs
- National Directories
- After School Programs
- Alternative Schools
- The Arts
- At-Risk Students
- Camps
- Camp Services
- Colleges & Universities
- Counties
- Driving Schools
- Educational Businesses
- Financial Aid
- Higher Education
- International Programs
- Jewish Community Centers
- K-12 Schools
- Language Studies
- Libraries
- Organizations
- Preschools
- Professional Development
- Prom Services
- School Assemblies
- School Districts
- School Field Trips
- School Health
- School Supplies
- School Travel
- School Vendors
- Schools Worldwide
- Special Education
- Special Needs
- Study Abroad
- Teaching Abroad
- Volunteer Programs
- Youth Sports
- For Schools
- Academic Standards
- Assembly Programs
- Blue Ribbon Schools Program
- Educational Accreditation
- Educational Television Channels
- Education in the United States
- History of Education in the United States
- Reading Education in the U.S.
- School Grades
- School Meal Programs
- School Types
- School Uniforms
- Special Education in the United States
- Systems of Formal Education
- U.S. Education Legislation
- For Teachers
- Academic Dishonesty
- Childcare State Licensing Requirements
- Classroom Management
- Education Subjects
- Educational Videos
- Interdisciplinary Teaching
- Job and Interview Tips
- Lesson Plans | Grades
- Professional Development
- State Curriculum Standards
- Substitute Teaching
- Teacher Salary
- Teacher Training Programs
- Teaching Methods
- Training and Certification
- For Students
- Academic Competitions
- Admissions Testing
- At-Risk Students
- Career Planning
- College Admissions
- Drivers License
- Educational Programs
- Educational Television
- Educational Videos
- High School Dropouts
- Higher Education
- School Health
- Senior Proms
- Sex Education
- Standardized Testing
- Student Financial Aid
- Student Television Stations
- Summer Learning Loss